Help with Capillary Physiology - Anatomy

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Question

Which scenario causes fluid to return to the capillaries from the interstitial fluid?

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Answer

Fluid movement into and out of capillaries is mainly dependent on two forces: hydrostatic pressure and osmotic pressure. Hydrostatic pressure is determined by fluid volume and the pressure of the fluid against the capillary walls. Osmotic pressure is determined by osmotic gradient, pulling water in the direction of higher protein concentration. Osmotic pressure is largely directed into the capillary due to the high concentration of albumin in the plasma. The osmotic pressure outside of the capillary remains relatively constant, however, as the capillary moves from the arteriole end to the venule end the hydrostatic pressure drops significantly. Eventually, the osmotic pressure in the interstitium becomes greater than the hydrostatic pressure in the capillary, and fluid returns to the capillaries.

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