Other Kinetics Principles Practice Test

Which of the following does not increase reaction rate?

Suppose that an enzyme has a critical functional group in its active site that is heavily involved in carrying out the catalytic mechanism. To perform its role in catalyzing its target reaction, this particular functional group must be able to accept a proton from the intermediate during the process. If the pKa of this functional group is equal to 7.0, then what percentage of the total enzyme active sites for this enzyme would be in the active form in a solution in which the pH is equal to 6.4?