Nonsterile Compounding>Calculation Conversion Practice Test

Your pharmacy receives a prescription for hydrocortisone topical lotion. The formula directs: Hydrocortisone powder 1.2 g, isopropyl alcohol sufficient to wet, propylene glycol 10 mL, and lotion base q.s. to 120 mL. The technician weighs 1.2 g of hydrocortisone, wets with a small amount of alcohol, mixes with propylene glycol, then brings to final volume with lotion base to 120 mL. Assume no significant volume change from dissolution or loss during compounding. The pharmacist will label the preparation based on the drug amount and final volume.

A pharmacist prepares an oral suspension of metronidazole for a pediatric patient. The formula calls for metronidazole bulk powder, a wetting agent, and a 1:1 mixture of Ora-Plus and Ora-Sweet, then quantity sufficient with Ora-Sweet to a total volume of 240 mL. The technician accurately weighs 1.2 g of metronidazole powder, wets and triturates it, then adds 60 mL of Ora-Plus and 60 mL of Ora-Sweet. The mixture is transferred to a graduated cylinder and brought to volume with additional Ora-Sweet to 240 mL. Assume no significant volume displacement from the powder.