Pharmacology>Ddi Identification Practice Test

A 62-year-old man presents with productive cough and low-grade fever. His history includes hypertension, type 2 diabetes, and hyperlipidemia. Current medications: simvastatin 40 mg at bedtime, metformin 1000 mg twice daily, and lisinopril 20 mg daily. The clinician diagnoses community-acquired pneumonia and prescribes clarithromycin 500 mg twice daily for 7 days. Vitals: BP 138/82 mm Hg, HR 78 bpm, RR 18, Temp 100.4 F, SpO2 96% on room air. Labs today: SCr 1.0 mg/dL, AST 28 U/L, ALT 32 U/L, CK 120 U/L, A1C 7.6 percent. He denies muscle pain currently but remains physically active. The pharmacist is asked to evaluate for drug interactions and recommend any changes before dispensing the antibiotic.

A 58-year-old man with hyperlipidemia and hypertension presents for follow-up after an urgent care visit for sinusitis. Home medications: simvastatin 40 mg nightly, lisinopril 20 mg daily, hydrochlorothiazide 25 mg daily. He was started on clarithromycin 500 mg twice daily yesterday. Vitals: BP 138/84, HR 76, RR 16, Temp 98.4 F. Labs: CK 112 U/L, AST 24 U/L, ALT 22 U/L, SCr 0.9 mg/dL (eGFR 95 mL/min/1.73 m2), K 4.2 mEq/L. He reports new mild diffuse muscle aches since last night. He denies chest pain or dark urine.