Human Anatomy and Physiology : Injuries and Disorders

Study concepts, example questions & explanations for Human Anatomy and Physiology

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Example Questions

Example Question #3 : Immune System

Which of the following does not release histamine?

Possible Answers:

Mast cell

Platelet

Neutrophil

Basophil

Correct answer:

Neutrophil

Explanation:

Mast cells are perhaps the best-known producers of histamine. Basophils also release histamine and contribute to the inflammatory response, while platelets are also capable of releasing histamine. Neutrophils are best-known for their phagocytic properties, and do not produce histamine.

Example Question #1 : Help With Immune System Injuries And Disorders

Which of the following causes edema during inflammation?

Possible Answers:

Decreased hydrostatic pressure in the venules

Increased oncotic pressure in the arterioles

Increased hydrostatic pressure in the arterioles

Increased oncotic pressure in the venules

Correct answer:

Increased hydrostatic pressure in the arterioles

Explanation:

There are two primary types of pressure: hydrostatic pressure is the result of fluid volume pressing on a physical boundary, while oncotic pressure is the pulling force of protein concentrations causing watter diffuse across a membrane. During an inflammation response, fluid is allowed to leak out of arterioles and capillaries resulting in increased hydrostatic pressure in the interstitium. Edema is the accumulation of fluid in the interstitium.

All the other answers cause fluid to return to the vessel, rather than exit it.

Example Question #4 : Immune System

Which of the following do NSAIDS effect?

Possible Answers:

Leukotriene

Phospholipase C

Lipoxygenase

COX-1 

Correct answer:

COX-1 

Explanation:

NSAIDs inhibit COX-1, inhibiting the formation of prostanglandins.

Example Question #3 : Immune System

What is sarcoidosis?

Possible Answers:

A form of cancer

Another term for tuberculosis

A disorder of the immune system cells that cause inflammation which leads to the formation of granulomas

A digestive disorder that leads to irritable bowels

Correct answer:

A disorder of the immune system cells that cause inflammation which leads to the formation of granulomas

Explanation:

Sarcoidosis is a disease of unknown cause that leads to inflammation. The immune cells that cause inflammation do not dissipate and instead, create clusters called granulomas. Not all cases of sarcoidosis require treatment.

Example Question #4 : Immune System

What is the difference between MRSA and other Staphylococcus infections?

Possible Answers:

They are the same thing

Other Staphylococcus infections are more serious

MRSA is antibiotic resistant

MRSA is easier to treat

Correct answer:

MRSA is antibiotic resistant

Explanation:

MRSA stands for methicillin-resistant Staphylococcus aureus. It is often seen in hospitals or long term care facilities. It can be treated using other antibiotics or is sometimes drained and left to heal without other intervention. 

Example Question #5 : Immune System

What are some of the symptoms of African sleeping sickness?

Possible Answers:

Wet cough, excessive mucous secretion from nose and eyes, and headache

Irritability, insomnia, uncontrollable bleeding

Fever, severe headache, irritability, extreme fatigue, swollen lymph nodes, and aching muscles

Severe fever, hacking cough, and blood in stools

Correct answer:

Fever, severe headache, irritability, extreme fatigue, swollen lymph nodes, and aching muscles

Explanation:

African Sleeping Sickness, caused by a parasite spread by the Tsetse Fly, has several symptoms that appear about 1-3 weeks after being bitten by the fly. The most common symptoms are fevers, extreme fatigue, muscle aches, irritability, swollen lymph nodes, and severe headaches. 

Example Question #6 : Immune System

What insect carries the parasite responsible for African sleeping sickness?

Possible Answers:

Tsetse fly

Lone star tick

Mosquito

Botfly

Correct answer:

Tsetse fly

Explanation:

Africa sleeping sickness, also known as African trypanosomosis, is caused by a parasite. The parasite, Trypanosoma brucei rhodesiense, is carried by the Tsetse fly. The fly bite is the mechanism for the parasite entering the body. There are two variations of sleeping sickness, East African and West African. 

Example Question #5 : Immune System

Name the protein most directly involved leukocyte rolling during diapedesis.

Possible Answers:

CD31

ICAMs

Integrins

Selectins

Correct answer:

Selectins

Explanation:

Selectins are most involved in the process of leukocyte rolling—or diapedesis—while ICAMs and integrins are involved in leukocyte firm and CD31 is involved in leukocyte transmigration.

Example Question #131 : Injuries And Disorders

Endothelial cell retraction involves which of the following?

Possible Answers:

Il-1

Histamine

Neutrophils

TNF-alpha

Correct answer:

Histamine

Explanation:

During endothelial cell retraction, gaps form between the cells as their cytoskeletons are rearranged to decrease the cell's area. This is a result of histamine, which causes increased vascular permeability; endothelial cell retraction allows fluids to pass between the cells, contributing to the inflammatory effects of histamine.

Example Question #132 : Injuries And Disorders

Which of the following tests best detects antigens in serum?

Possible Answers:

Agglutination test

ELISA test

DNA microarray

Precipitation test

Correct answer:

ELISA test

Explanation:

An ELISA test would best look at antigens present in serum by using secondary antibodies to bind to antigen-antibody complex and change color, showing if an antigen is present. DNA microarray would just show genes activated. Precipitation and agglutination reactions are not as sensitive as ELISA.

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