MCAT Biology : Biology

Study concepts, example questions & explanations for MCAT Biology

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Example Questions

Example Question #4 : Circulatory System

Which of the following statements most accurately describes the cardiac output (CO) of the heart?

Possible Answers:

Cardiac output is the volume of blood pumped by a ventricle every minute (volume/min)

Cardiac output is the same as heart rate (beats/min)

Caridac output is the same as stroke volume (volume of blood pumped from each beat)

Cardiac output is equal to the mean arterial pressure (MAP)

Correct answer:

Cardiac output is the volume of blood pumped by a ventricle every minute (volume/min)

Explanation:

Cardiac output is the product of heart rate (HR) and stroke volume (SV). Heart rate is equal to beats per minute, while stroke volume is equal to volume per beat. The "beat" units cancel, and leave the cardiac output equal to volume per minute.

cardiac output = (beats/min) * (volume/beat) = volume/min. 

Example Question #2 : Circulatory System

Cardiac muscle cells are electrically linked to each other through which of the following?

Possible Answers:

Cholinergic receptors

Synaptic junctions

Axonal extensions

Gap junctions

Pressure receptors

Correct answer:

Gap junctions

Explanation:

Electrical coupling of cells is mediated through gap junctions—ions are able to immediately flow through adjacent cells through these transmembrane protein channels. Cardiac muscle requires such syncytial connections in order to most effectivey synchronize muscle contraction.

Neurotransmitters, synaptic junctions, and cholinergic receptors would necessitate a nervous system communication, but the heart is electrically-coupled without neural mediation. Pressure receptors are not involved in cardiac muscle activity.

Example Question #4 : Heart

Which cardiac valve prevents backflow of blood from the left ventricle into the left atrium? 

Possible Answers:

Mitral Valve 

Tricuspid Valve 

Pulmonary Valve

Aortic Valve

Correct answer:

Mitral Valve 

Explanation:

This a simple anatomy question. The mitral (bicuspid) valve lies between the left atrium and ventricle, therefore the answer must be the mitral valve. The tricuspid valve lies between the right atrium and ventricle.

Example Question #7 : Circulatory System

What are the valves between the right atrium and right ventricle, and between the left atrium and left ventricle, respectively?

Possible Answers:

Tricuspid valve; mitral valve

Bicuspid valve; tricuspid valve

Mitral valve; pulmonary valve

Aortic valve; bicuspid valve

Correct answer:

Tricuspid valve; mitral valve

Explanation:

The valve between the right atrium and ventricle is the tricuspid valve. The valve between the left atrium and ventricle is called the bicuspid, or mitral, valve. "Bicuspid" and "mitral" can be used interchangeably.

The pulmonary valve connects the right ventricle with the pulmonary artery, while the aortic valve connects the left ventricle with the aorta.  

Example Question #8 : Circulatory System

Which is the only valve in the heart to have two operational flaps?

Possible Answers:

Mitral valve

Semilunar valve

Pulmonary valve

Tricuspid valve

Correct answer:

Mitral valve

Explanation:

The semilunar valves refer to the aortic valve and pulmonary valve, both of which have three flaps. The atrioventricular valves separate the atria from the ventricles. The right side of the heart is separated by the tricuspid valve, while the left is separated by the bicuspid, or mitral, valve. The mitral valve is the only heart valve with two flaps.

Example Question #9 : Circulatory System

When blood moves from the right atrium to the right ventricle, it must pass through which heart valve?

Possible Answers:

The tricuspid valve

The semilunar valve

The mitral valve

It does not pass through any valve

The pulmonary valve

Correct answer:

The tricuspid valve

Explanation:

When blood passes from the right atrium into the right ventricle, it must pass through the tricuspid valve.

The mitral, or bicuspid, valve separates the left atrium and ventricle. The semilunar valves are the aortic and pulmonary valves. The aortic valve separates the left ventricle and aorta, while the pulmonary valve separates the right ventricle and pulmonary arteries.

Example Question #1 : Heart

The firing of which group of cells initiates contraction of the left and right ventricles?

Possible Answers:

Bundle of His 

Atrioventricular node

Purkinje fibers

Sinoatrial node

Correct answer:

Atrioventricular node

Explanation:

After axons from the sinoatrial node flow through the atria to cause atrial contraction, the depolarization pauses in the atrioventricular node. Once the atrioventricular node depolarizes, the electrical signal travels though the bundle of His to the walls of the ventricles via purkinje fibers. The atrioventricular node initiates ventricular contraction, the bundle of His carries the signal, and the purkinje fibers allow for synchronized contraction of different regions of the ventricular wall.

Example Question #831 : Biology

Which nerve, as part of the parasympathetic nervous system, serves to decrease heart rate?

Possible Answers:

Radial nerve

Femoral nerve

Subcostal nerve

Vagus nerve

Correct answer:

Vagus nerve

Explanation:

The vagus nerve is a major nerve of the parasympathetic nervous system, responsible for mediating numerous responses in the body. In relation to the heart, the vagus nerve provides constant inhibition to the sinoatrial node, slowing the heart rate. The sinoatrial node naturally fires at about 80 to 100 beats per minute, while a healthy resting heart rate is closer to 60 due to innervation by the vagus nerve.

The radial nerve is located in the forearm; the femoral nerve is located in the thigh; the subcostal nerve is located along the lower ribs.

Example Question #832 : Biology

Which group of cells is responsible for the autoregulation of heart contraction?

Possible Answers:

Atrioventricular node

Sinoatrial node

Purkinje fibers

Bundle of His

Correct answer:

Sinoatrial node

Explanation:

The heart beats automatically through stimulation from the sinoatrial node. The group of neurons found in this node depolarize in a coordinated, spontaneous manner to allow for the contraction of the atria and ventricles in the heart. Without the sinoatrial node, heart contraction may be possible, but it would not be regular and would require additional regulation.

Depolarization of the sinoatrial node specifically leads to atrial contraction. The signal is then transmitted through the atrioventricular node and bundle of His to the purkinje fibers, which coordinate the contraction of the ventricles.

Example Question #13 : Circulatory System

A patient presents with signs of fatigue and elevated heart rate. It is found that the patient's blood supply is not fully saturated with oxygen because not all of the blood is passing through the patient's lungs. It is found that the patient has a birth defect. Which structure in the patient originally diverted blood from the lungs while the patient was a fetus?

Possible Answers:

Ductus venosus

Ductus arteriosus

Ductus venosus and foramen ovale

Foramen ovale

Foramen ovale and ductus arteriosus

Correct answer:

Foramen ovale and ductus arteriosus

Explanation:

In a fetus, there are three fetal shunts: the ductus arteriosus, the ductus venosus, and the foramen ovale. Failure to fully close the foramen ovale during birth will allow blood to shunt directly from the right atrium to the left atrium, diverting the blood from the lungs. The ductus arteriosus also shunts blood away from the fetal non-functional lungs, allowing it to pass directly from the pulmonary artery to the aorta. Additionally, after birth, the ductus arteriosus becomes the ligamentum arteriosum.

Conversely, the ductus venosus is a structure in the fetus that diverts blood away from the fetal liver.

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