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Example Questions
Example Question #1 : Reactions
Which of the following statements is true concerning the Hofmann elimination reaction?
Possible Answers:
The Zaitsev product is favored in the elimination reaction
The least substituted alkene is the major product in the reaction
The ammonium is eliminated following an E1 mechanism
The quaternary ammonium salt is a poor leaving group
Correct answer:
The least substituted alkene is the major product in the reaction
Explanation:
The Hofmann product is the most favored product in a Hofmann elimination reaction. The reaction follows an E2 mechanism, where a quaternary ammonium salt is able to be removed from a hydrocarbon, resulting in an alkene product. This reaction results in the least substituted alkene being the primary product.
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